focalinterest.net

AI Summary of Scholarly Research

This page presents an AI-generated summary of a published research paper. The original authors did not write or review this article. [See full disclosure ↓]

Peripheral craniofacial osteomas were most common in the frontal bone

Written by

editor@focalinterest.com

in

Research area:medicine-clinicaloncology

What the study found

The study found that craniofacial osteomas are benign, slow-growing bony tumors that were most often located in the frontal bone and occurred more frequently in females. The authors also report that imaging-based diagnosis, tailored surgery, and selective genetic testing were associated with favorable postoperative outcomes in this patient group.

Why the authors say this matters

The authors say the study addresses the limited availability of standardized diagnostic and treatment protocols for craniofacial osteomas. They conclude that combining imaging, chosen surgical techniques, and selective genetic testing allows for accurate evaluation and effective treatment.

What the researchers tested

The researchers conducted a retrospective review of 141 patients with craniofacial osteomas treated at Kyungpook National University Hospital between October 2011 and September 2025. All patients had clinical examinations and 3-dimensional computed tomography for diagnosis, and some underwent surgical excision by direct, endoscopic, or bicoronal approaches. Whole exome sequencing, a method that examines many genes at once, was performed in patients with multiple large osteomas to evaluate EXT1, EXT2, APC, MSH2, and MLH1 genes linked to Gardner syndrome.

What worked and what didn't

A total of 148 osteomas were identified, with the frontal bone as the most common site (60.1%), followed by the parietal, mandibular, and occipital bones. Females accounted for 79.1% of cases, genetic testing found no pathogenic variants related to Gardner syndrome, and no recurrences were observed during 6 months of follow-up.

What to keep in mind

The study was retrospective and came from a single hospital, so the findings reflect one clinical setting. The abstract does not describe longer-term follow-up beyond 6 months, and it does not provide detailed limitations beyond the available summary.

Key points

  • Craniofacial osteomas were most commonly found in the frontal bone.
  • Females made up 79.1% of the cases.
  • No pathogenic variants related to Gardner syndrome were found in the genetic testing reported.
  • No recurrences were observed during 6 months of follow-up.
  • The study used clinical exams, 3-dimensional computed tomography, surgery, and selective whole exome sequencing.

Disclosure

Research title:
Peripheral craniofacial osteomas were most common in the frontal bone
Authors:
Jung-Eun Moon, Hyun Su Kang, Yong June Chang, Ki-Su Park, Mansoo Suh, Jeong Yeop Ryu, Kang Young Cho, Jung Dug Yang, Ho Yun Chung, Joon Seok Lee
Institutions:
Kyungpook National University, Kyungpook National University Chilgok Hospital, Kyungpook National University Chilgok Hospital, Kyungpook National University Chilgok Hospital, Kyungpook National University Chilgok Hospital, Kyungpook National University Chilgok Hospital, Kyungpook National University Chilgok Hospital, Kyungpook National University Chilgok Hospital, Kyungpook National University Chilgok Hospital, Kyungpook National University Chilgok Hospital, Kyungpook National University Hospital, Kyungpook National University Hospital, Kyungpook National University Hospital, Kyungpook National University Hospital, Kyungpook National University Hospital, Kyungpook National University Hospital, Kyungpook National University Hospital, Kyungpook National University Hospital, Kyungpook National University Hospital
Publication date:
2026-03-30
DOI:
10.1097/scs.0000000000012685
OpenAlex record:
View
AI provenance: This post was generated by gpt-5.4-mini (OpenAI). The original authors did not write or review this post.

More posts