Category: Biology & Genetics
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Wild tomato genomes show structural variants affect recombination
This research indicates that wild tomato genome assemblies reveal how repeat content and structural variants act as barriers to recombination, while recombination differs between female and male meiosis.
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Refined hydrodynamic models add lipid alignment to bilayer descriptions
This research indicates that lipid bilayer models can be extended to include molecular alignment while still recovering known surface (Navier–)Stokes–Helfrich models in the fully ordered case.
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Hydrogels may improve skeletal muscle repair after volumetric muscle loss
This research indicates that hydrogels, especially natural, synthetic, and peptide-based systems, are being developed to better support skeletal muscle repair after volumetric muscle loss by filling defects and providing regenerative cues.
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CASP5C promotes Wnt signaling in human intestinal epithelium
This research indicates that the CASP5C isoform of caspase 5 promotes Wnt signaling in the human intestinal epithelium by cleaving APC and helping sustain epithelial renewal.
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Polyphenols alter κ-carrageenan hydrogel mechanics and disintegration
This research indicates that plant-derived polyphenols can reprogram kappa-carrageenan hydrogels in a structure-dependent way, changing their strength, thermal behavior, adhesion, and disintegration.
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New pyrazoloquinazoline compounds showed mixed TLR7/8 activity
This research indicates that a pyrazolo[1,5-c]quinazoline compound showed moderate agonist activity for TLR7 and TLR8, and that three modified compounds became dual TLR7/8 antagonists.
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Perspective links biofilm rheology to space-environment concerns
This research indicates that bacterial suspensions and biofilms have rheological properties that may be influenced by gravity and flow, and that understanding these properties may help address biofouling in space and on Earth.
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Network microscopic properties limit phase separation domain size
This research indicates that finite-sized phase-separated domains in elastic polymer networks are controlled by microscopic strand and network length scales more than by bulk elasticity.
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ATF4 is required for upper-layer cortical neuron development
This research indicates that activating transcription factor 4 is an essential regulator of DNA damage repair and is required for the development of upper layer 2/3 neurons marked by CUX2.
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Dwarf Cavendish and Red Dacca differ in fruit and biochemical traits
This research indicates that Dwarf Cavendish banana fruits were better in pomological traits, while Red Dacca showed higher biochemical and functional properties.
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