What the study found
The study describes a rare benign soft-tissue tumor called collagenous fibroma in the periocular region, with metaplastic ossification meaning bone formation within the tumor. The case showed that this lesion can look similar to other fibrous or bone-forming tumors.
Why the authors say this matters
The authors conclude that recognizing this pattern matters because the tumor is benign but may mimic more aggressive lesions, which can lead to diagnostic confusion and unnecessary aggressive management of periocular lesions.
What the researchers tested
The researchers reported a case of a 49-year-old woman with a small, firm mass in the lateral eyebrow region. Magnetic resonance imaging and histopathologic examination were used to evaluate the lesion.
What worked and what didn't
Imaging showed a well-circumscribed lesion with low signal intensity, which raised concern for other fibrous or osseous tumors. Histopathology identified a hypocellular, collagen-rich stroma with sparse spindle-to-stellate fibroblastic cells and discrete islands of mature lamellar bone, supporting the diagnosis of collagenous fibroma with metaplastic ossification. Complete local excision was curative, and there was no recurrence.
What to keep in mind
This is a single case report, so the available summary does not provide broader frequency estimates or comparative outcomes. The abstract does not describe additional limitations beyond the rarity of the lesion and the possibility of diagnostic confusion.
Key points
- A rare benign tumor, collagenous fibroma, was found in the periocular region.
- The tumor included metaplastic ossification, meaning bone formed within the lesion.
- MRI showed a well-circumscribed low-signal lesion that raised concern for other fibrous or osseous tumors.
- Histopathology confirmed a collagen-rich, low-cellularity tumor with mature lamellar bone.
- Complete local excision was curative, with no recurrence reported.
Disclosure
- Research title:
- Periocular collagenous fibroma with bone formation described
- Authors:
- Jeeyoon Kim, Yerin Kim, Jongweon Shin
- Institutions:
- Catholic University of Korea, St. Mary's Hospital
- Publication date:
- 2026-03-30
- OpenAlex record:
- View
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