Focal Interest
Focal Interest

Sulfonyl

  1. Functional groups strongly affect amino acid LC-MS derivatization
    Systematic evaluation of derivatization agents for LC-MS amino acid analysis identifies isoquinoline-6-carboxylic acid NHS ester as optimal, achieving nanomolar sensitivity and long-term stability.
  2. Modular synthesis of CF3/CHF2 dihydroquinoline sulfonyl fluorides
    Modular synthesis of CF3/CHF2-substituted dihydroquinoline sulfonyl fluorides via [4+2] cycloaddition and sulfur(VI) fluoride exchange without transition metal catalysis.