Tuberculosis Research and Epidemiology

Rapid PCR testing on tongue swabs shows promise for tuberculosis diagnosis in sputum-scarce patients, with high specificity but limitations in detecting low bacillary loads.

Case report of ICI-induced TB reactivation managed with short-course anti-TB therapy followed by continued checkpoint inhibitor monotherapy, suggesting personalized management alternatives to.

Severe alopecia developed in a 22-year-old woman with isoniazid-monoresistant tuberculosis after starting treatment. Hair regrowth occurred after discontinuing isoniazid, highlighting the.

Atypical mycobacterial infection in adolescent presenting with atrophic plaques and concurrent epidermal inclusion cyst. Case report highlights diagnosis and antibiotic resistance considerations.

XGBoost machine learning model demonstrates superior accuracy for monthly tuberculosis forecasting in coastal urban environments compared to traditional ARIMA and Prophet approaches.

Study of 311 adults with trace-positive TB tests shows 20% culture-confirmed disease at enrollment and identifies clinical predictors to guide treatment decisions in settings with uncertain TB status.

Study of 38,928 TB patients in Shenyang reveals 56.65% experience consultation delays. Female, elderly, ethnic minority, and farmer patients at highest risk. Targeted interventions needed.

Population-based whole-genome sequencing study of 206 MDR/RR-TB isolates in China reveals compensatory mutations have limited impact on transmission clustering.

Systematic review of 21 tuberculous meningitis diagnostic scoring systems, identifying 4 with external validation and recommending Thwaites and Marais scores as first-line screening tools.

Nationwide Korean seroprevalence survey of Mycobacterium bovis and avium in domestic sows and wild boars, revealing 4.54-5.91% M. bovis and 7.71-10.10% M. avium exposure.

Explore CBC-derived ratios for tuberculosis diagnosis in rheumatic disease patients. Study shows limited standalone accuracy but potential as adjunctive screening tools alongside microbiological.

Machine learning analysis of environmental and socioeconomic determinants of tuberculosis incidence in Taiwan, identifying key drivers and nonlinear relationships for disease forecasting.

Nine-month all-oral TB regimens show 89.5% durable three-year cure rates but persistent linezolid neuropathy affects 22.6% of patients, raising safety concerns.

Nanopore-based targeted sequencing demonstrates 93% sensitivity and specificity for detecting Mycobacterium tuberculosis and drug resistance from non-sputum specimens in multicenter Chinese study.

Urine metabolomics via NMR spectroscopy shows promise for early diagnosis of paediatric tuberculosis, achieving 97% accuracy in distinguishing active TB from latent infection.

Learn about an atypical childhood TB case presenting as a mediastinal cyst without cough. Explores diagnostic challenges, tissue confirmation methods, and clinical management considerations.

PET/CT-derived multivariate lesion profiles in M. tuberculosis–infected marmosets predict clinical regimen performance, distinguish cavitary granuloma responses, and outperform bacterial burden.