What the study found
The authors report a rare benign soft-tissue tumor called collagenous fibroma in the periocular region, meaning the area around the eye, with metaplastic ossification, or bone formation within the tumor. The lesion could resemble other fibrous or osseous tumors on imaging.
Why the authors say this matters
The authors conclude that recognizing this benign tumor is important because it can be confused with more aggressive lesions. They say this may help avoid diagnostic confusion and unnecessary aggressive management of periocular lesions.
What the researchers tested
The researchers described a single case of a 49-year-old woman with a small, firm mass in the lateral eyebrow region. She underwent magnetic resonance imaging and histopathologic examination after complete local excision.
What worked and what didn't
Magnetic resonance imaging showed a well-circumscribed lesion with low signal intensity, which raised concern for other fibrous or osseous tumors. Histopathology showed a hypocellular, collagen-rich stroma with sparse spindle-to-stellate fibroblastic cells and discrete islands of mature lamellar bone, consistent with collagenous fibroma with metaplastic ossification, and complete local excision was curative with no recurrence.
What to keep in mind
This is a single case report, so the findings are limited to one patient. The abstract does not describe longer follow-up beyond no evidence of recurrence after excision.
Key points
- The case involved a rare collagenous fibroma in the periocular region.
- The tumor contained metaplastic ossification, meaning bone formed inside the lesion.
- Imaging suggested a possible fibrous or osseous tumor before diagnosis.
- Microscopy confirmed a collagen-rich, low-cellularity tumor with mature bone islands.
- Complete local excision was curative, with no recurrence reported.
Disclosure
- Research title:
- Periocular collagenous fibroma with bone was benign
- Authors:
- Jeeyoon Kim, Yerin Kim, Jongweon Shin
- Institutions:
- Catholic University of Korea, Catholic University of Korea, Catholic University of Korea, St. Mary's Hospital
- Publication date:
- 2026-03-30
- OpenAlex record:
- View
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