Tag: DNA Repair Mechanisms
Talazoparib resistance in triple-negative breast cancer linked to BRN2 and SHLD2
Resistance mechanisms to PARP inhibitor therapy in BRCA-mutant breast cancer
DNA damage burden causes selective CUX2 neuron loss in neuroinflammation
DNA damage burden drives selective loss of cortical neurons in multiple sclerosis
PAF15-PCNA exhaustion limits strand-specific DNA replication control
How a protein complex limits DNA replication when origins fire excessively
Mitotic repair pathway drives chromoanasynthesis
A mitotic DNA repair process explains how complex chromosome rearrangements form in cancer
Human Pol-PCNA binds DNA in an unexpected extra site
Structural models need revision based on unexpected enzyme behavior in laboratory tests
SFPQ helps protect repeat DNA from R-loop damage
A protein protects repetitive DNA regions from dangerous RNA-DNA structures
