What the study found
The study found that an azobenzene-grafted cellulose sorbent called Cell-Azo could bind amphetamine and release it when exposed to light. The authors report that the material showed reversible light-driven switching and could be used for solid-phase extraction of amphetamine.
Why the authors say this matters
The authors conclude that Cell-Azo may be an efficient, green, and controllable alternative for trace amphetamine analysis in complex samples. They present the light-controlled release as the key feature that enables this use.
What the researchers tested
The researchers made Cell-Azo by grafting azobenzene onto cellulose through atom-transfer radical polymerization. They verified the material with FT-IR, XPS, and UV-vis spectroscopy, then tested adsorption behavior, light-triggered release, and a dispersive solid-phase extraction method coupled with HPLC-UV.
What worked and what didn't
The sorbent reached a maximum adsorption capacity of 19.86 mg per g at pH 9.0. UV light triggered amphetamine release with 90.54% desorption efficiency, while less than 35% desorbed in the dark. The analytical method showed linearity from 0.05 to 2.00 mg per L, a limit of detection of 7 micrograms per L, a limit of quantification of 23.33 micrograms per L, and precision with RSD below 5.1%; in spiked urine, recoveries were 69.53-75.68%.
What to keep in mind
The abstract does not describe detailed limitations beyond the reported performance in spiked urine samples. The results are based on the specific analyte amphetamine and the conditions tested in this study.
Key points
- Cell-Azo is a cellulose-based sorbent modified with azobenzene.
- Light exposure switched the material between binding and release of amphetamine.
- The maximum adsorption capacity was 19.86 mg per g at pH 9.0.
- UV light produced 90.54% desorption efficiency, compared with less than 35% in the dark.
- The HPLC-UV method showed a detection limit of 7 micrograms per L and recoveries of 69.53-75.68% in spiked urine.
Disclosure
- Research title:
- Light-controlled cellulose sorbent enabled amphetamine extraction
- Authors:
- Yuhong Xie, Rui Zhang, Y Liu, Yuancai Lv, Xiaoxia Ye, Liang Song, Chunxiang Lin, Minghua Liu
- Institutions:
- Fuzhou University, Fuzhou University, Fuzhou University, Fuzhou University, Fuzhou University, Fuzhou University, Fuzhou University, Fuzhou University, Putian University
- Publication date:
- 2026-02-27
- OpenAlex record:
- View
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