Category: Biology & Genetics
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Tmem178 suppresses NLRP3 inflammasome activation in osteoclasts
This research indicates that Tmem178 limits calcium influx in osteoclasts and thereby suppresses NLRP3 inflammasome activation.
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Implant design must account for surgical placement and removal
This research indicates that implantable artificial muscles should be designed around how they are deployed, sterilized, protected from contamination, used, and removed.
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Autonomous electron-beam fabrication controlled tailored defects in 2D materials
This research indicates that a fully autonomous approach can fabricate atomic-level defects in two-dimensional materials using machine learning-enabled scanning transmission electron microscopy.
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Genetic testing choices in pediatric endocrine disorders
This research indicates that selecting genetic tests in pediatric endocrinology should be guided by clinical phenotype, biochemical findings, and the suspected genetic mechanism.
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Earliest octopuses were giant Cretaceous marine predators
This research indicates that the earliest finned octopuses were large invertebrate top predators in Late Cretaceous oceans, with fossil jaws suggesting hard-shelled prey crushing and possible advanced intelligence.
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Probiotic supplementation improved postoperative antioxidant status
This research indicates that probiotic supplementation may improve postoperative antioxidant status in patients undergoing open-heart surgery.
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Astrocytes form specific, plastic networks across the mouse brain
This research indicates that gap junction-coupled astrocytes form selective, plastic networks that connect specific brain regions, including distant regions across hemispheres.
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Silicon effects on peanut yield depended on microbial inoculant
This research indicates that silicon application changed peanut biomass and yield responses depending on whether the plants were inoculated with Azospirillum or Bradyrhizobium.
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SIDE generates realistic low-energy biomolecular transition paths
This research indicates that a Langevin bridge-based framework can generate smooth, low-energy transition paths between protein conformations and often recover experimentally supported intermediate states.
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Fibrosis-associated peptides identified as therapeutic targets in lung fibrosis
This research indicates that profiling the major histocompatibility complex class I immunopeptidome in pulmonary fibrosis can help identify therapeutic peptide targets and translatable antifibrotic immunotherapies.
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