Category: Clinical Medicine & Care
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Mitotic MM-BIR drives chromoanasynthesis in human cells
This research indicates that chromoanasynthesis is generated by mitotic microhomology-mediated break-induced replication, involving a collaboration between microhomology-mediated end-joining and break-induced replication.
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Romanian intensivists report communication and system barriers to organ donation
This research indicates that Romanian intensive care physicians see educational, organizational, and system-level barriers as limiting organ donation performance.
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Periodontitis is associated with higher acute myocardial infarction risk
This research indicates that periodontitis is associated with a higher risk of acute myocardial infarction, especially when periodontal inflammation and tissue destruction are more severe.
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Belgian adaptation of nurse-led eHealth monitoring required local changes
This research indicates that the SMILe integrated care model needed context-specific adaptation for local daily care, including use of the local eHealth platform and fewer advanced practice nurse sessions.
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Ultrasound and radiography vary in usefulness for spaceflight conditions
This research indicates that ultrasound and radiography differ in how useful they are for diagnosing and managing NASA-listed in-flight medical conditions.
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BRN2 and SHLD2-linked resistance emerged during talazoparib treatment
This research indicates that neoadjuvant talazoparib resistance in BRCA1/2-mutant triple-negative breast cancer can arise through BRN2-driven activation of ATR, RAD51, and STAT3 pathways or through expansion of a Shieldin 2-deficient tumor subclone.
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Saffron floral residues showed antioxidant and antimicrobial activity
This research indicates that saffron tepal extracts contain phytochemicals with antioxidant and antimicrobial activity, and the authors suggest they may have pharmaceutical potential.
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HPTLC method validated for gentamicin sulphate in ointments
This research indicates that a stability-indicating high-performance thin-layer chromatography method can identify and quantify gentamicin sulphate in pharmaceutical ointments without interference from excipients or degradation products.
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Psychosocial factors remain central in lung transplant evaluation
This research indicates that psychosocial factors are associated with outcomes before and after lung transplantation, and that current guidance favors individualized assessment over broad contraindications.
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Persistent post-COVID respiratory symptoms linked to dysregulated breathing
This research indicates that in non-hospitalised adults with persistent respiratory symptoms after COVID-19, dysregulated breathing, deconditioning, and psychological distress were linked with symptom burden.
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