Category: Clinical Medicine & Care
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Urolithin A acts through multiple pathways linked to obesity and metabolism
This research indicates that urolithin A, a compound produced by certain gut microbes, may influence obesity and metabolic dysfunction through several coordinated biological pathways.
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COCs and progestin-only pills showed no consistent worsening of mood or sexual health
This research indicates that combined oral contraceptives and progestin-only pills do not show a consistent increase in negative psychological or sexual outcomes among women with endometriosis.
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Family navigation improved early intervention referral completion
This research indicates that family navigation improved early intervention referral completion and service initiation, but not service duration or child development, among mostly low-income urban Black children with suspected developmental delays.
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Jordanian premolar canals showed varied configurations on CBCT
This research indicates that maxillary premolars in a Jordanian subpopulation had diverse root and canal patterns, and Ahmed's classification described these patterns in more detail than Vertucci's classification.
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Neonatal nurses reported high perceived parental PTSD
This research indicates that neonatal nurses perceive high levels of trauma and post-traumatic stress disorder among parents of infants admitted to neonatal units in Northern Ireland.
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Olutasidenib showed disease control in some chondrosarcoma patients
This research indicates that olutasidenib was well tolerated and showed disease control in conventional chondrosarcoma, a rare cartilage cancer, in patients with recurrent or metastatic IDH1-mutated disease.
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Rare infraorbital swelling revealed as multiple myeloma relapse
This research indicates that unexplained facial swelling can be a rare sign of multiple myeloma relapse in a patient with a known plasma cell neoplasm.
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Lithium use in psychiatric emergencies needs careful, individualized assessment
This research indicates that lithium carbonate can be useful in psychiatric emergencies, but it should be used cautiously because of its slow onset, narrow therapeutic range, and need for monitoring.
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Baseline severity and prior care shaped CBT symptom change
This research indicates that in routine cognitive-behavioral therapy for depression and anxiety, higher starting symptom severity was linked to faster improvement, while prior psychiatric care or very long-term psychotherapy was linked to smaller gains.
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FMT plus immunotherapy showed clinical activity in NSCLC and melanoma
This research indicates that fecal microbiota transplantation before immunotherapy was clinically active in first-line non-small cell lung cancer and melanoma, and that removing certain bacterial species may be important for benefit.
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